MASTER SYLLABUS

2020-2021

A.	Academic Division: Health Sciences

B.	Discipline: Bioscience Technology

C.	Course Number and Title: BIOS 2530 Genetics

D.	Course Coordinator: Jason Tucker, M.S.

Assistant Dean: Melinda Roepke, MSN, RN

Instructor Information:

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E.	Credit Hours: 4

Lecture: 3

Laboratory: 3

F.	Prerequisites: BIOS 2410

Co-requisite: BIOS2590c

G.	Syllabus Effective Date: Fall, 2020

H.	Textbook(s) Title:

Essentials of Genetics

Authors: Klug, Cummings, Spencer, Palladino, & Killian

Copyright Year: 2020

Edition: 10th

ISBN: 9780134898414

Workbook(s) and/or Lab Manual:

Title: Genetics Laboratory Investigations

Authors: Thomas L Mertens, Robert L. Hammersmith

Copyright Year: 2015

Edition: 14th

ISBN: 9780321814173

J.	Course Description: During this course we will discuss the principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. The topics include: structure and function of genes, chromosomes and genomes, biological variation resulting from recombination, mutation, and selection, population genetics, use of genetic methods to analyze protein function, gene regulation and inherited disease.

K.	College-Wide Learning Outcomes:

College-Wide Learning Outcome	Assessments - - How it is met & When it is met
Communication – Written
Communication – Speech
Intercultural Knowledge and Competence
Critical Thinking	Homework assignments and Lab reports require assimilating data and drawing conclusions-Weekly. Critical Thinking VALUE Rubric: On Gene Expression, Regulation, and Development Lab Report (Week 6-9)
Information Literacy
Quantitative Literacy	Lab reports require simple statistics, and graphing Throughout the semester. Quantitative Literacy VALUE Rubric

L.	Course Outcomes and Assessment Methods:

Upon successful completion of this course, the student shall:

Outcomes	Assessments – How it is met & When it is met
Describe and differentiate between the steps of Mitosis and Meiosis.	Lab Reports-Week 1-2; First interim exam-Week 6; Final exam
Describe sex determination and the role of sex chromosomes.	Lab Report-Week 3; First interim exam-Week 6; Final exam
Synthesize the structure, replication and variation of DNA.	Lab Reports-Week 4-5; First interim exam-Week 6; Final exam
Describe gene expression, regulation and development.	Lab reports week 6-9; Second interim exam-week 12; Final exam
Illustrate the role of the cell cycle as it applies to cancer.	Second interim exam-week 12; Final exam
Demonstrate how recombinant DNA technology can be used to study current genetic topics.	Lab reports week 10-12; Second interim exam-week 12; Final exam
Integrate and relate knowledge of modern genetics to real life situations	Lab reports week 13-15; Final exam
Apply current research literature, information related to genetic issues in the mass media	Research paper on topics related to materials covered in class-Week10-12.

M.	Topical Timeline (Subject to Change):

Week	Topical Timeline
1, 2 and 3	Genes, Chromosomes, and Heredity Introduction to Genetics Mitosis and Meiosis Mendelian Genetics Sex Determination and Sex Chromosomes Chromosome Mutations: Variation in Number and Arrangement
4 and 5	DNA: Structure, Replication, and Variation DNA Structure and Analysis DNA Replication and Recombination DNA Organization in Chromosomes
6, 7, 8 and 9	Gene Expression, Regulation, and Development The Genetic Code and Transcription, Translation and Proteins Gene Mutation, DNA Repair, and Transposition Developmental Genetics Cancer and Regulation of the Cell Cycle
10, 11 and 12	Genomics Recombinant DNA Technology Genomics, Bioinformatics, and Proteomics Applications and Ethics of Genetic Engineering and Biotechnology Population and Evolutionary Genetics
13, 14 and 15	Special Topics in Modern Genetics Population and Evolutionary Genetics Epigenetics DNA Forensics Genomics and Personalized Medicine Genetically Modified Foods Gene Therapy

Lab (Will correspond roughly to Lecture Material Presentation Time Schedule)

Cell Reproduction: Mitosis.

Meiosis in Animals: Oogenesis and Spermatogenesis.

Sex Chromosomes and Gene Transmission.

The Sex Check: A Study of Sex Chromatin in Human Cells.

Linkage and Crossing Over.

The Genetic Material: Isolation of DNA.

Restriction Endonuclease Digestion and Gel Electrophoresis of DNA.

Amplification of DNA Polymorphisms by Polymerase Chain Reaction (PCR) and DNA Fingerprinting.

Transformation of E. coli.

Gene Action: Synthesis of Galactosidase in Escherichia coli.

Bacterial Mutagenesis.

Gene Recombination in Phage.

Polygenic Inheritance: Fingerprint Ridge Count.

Population Genetics: The Hardy-Weinberg Principle.

Population Genetics: The Effects of Selection and Genetic Drift.

N.	Course Assignments:

Research Paper (Week 10-12)

Lab Reports (Weekly)

Interim exams (Week 6 and 12)

Final Exam (Week 16)

O.	Recommended Grading Scale:

NUMERIC	GRADE	POINTS	DEFINITION
93–100	A	4.00	Superior
90–92	A-	3.67	Superior
87–89	B+	3.33	Above Average
83–86	B	3.00	Above Average
80–82	B-	2.67	Above Average
77–79	C+	2.33	Average
73–76	C	2.00	Average
70-72	C-	1.67	Below Average
67–69	D+	1.33	Below Average
63-66	D	1.00	Below Average
60-62	D-	0.67	Poor
00-59	F	0.00	Failure

P.	Grading and Testing Guidelines:

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Q.	Examination Policy:

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R.	Class Attendance and Homework Make-Up Policy:

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S.	Classroom Expectations:

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T.	College Procedures/Policies:

Important information regarding College Procedures and Policies can be found on the syllabus supplement located at

http://catalog.ncstatecollege.edu/mime/download.pdf?catoid=5&ftype=2&foid=3